[OA-17] The expression of CD15 in placental vessels belonging haemoglobin Bart's hydrops foetalis

Haemoglobin Bart can lead to hydrops foetalis (HF). Its placental findings include abnormally increased intermediate villi with immature endothelium. CD15 assists in diagnosis of delayed villous maturation by identification of foetoplacental endothelial immaturity. Thus, investigation of CD15 expression has benefit for understand pathophysiology of Hb Bart's HF. This study aimed to evaluate CD15 immunoreactivity in placental endothelium of Hb Bart's HF in comparison to that in other causes of HF. CD15 was performed in 14 cases of Hb Bart and 9 cases of HF by other causes...

[OA-05] Pancreatic islets of Langerhans and insolin secreting cells in haemoglobin Bart's hydrops foetalis

A finding of islet cell hyperplasia has been reported in infants of diabetic mothers and hydrops foetalis (HF), but no any report in haemoglobin (Hb) Bart's HF. The aim of this study was to analyse the morphometry of beta cells in Hb Bart. Pancreas from 10 Hb Bart cases and 9 controls were retrieved. ...